Stem Cell Therapy for Diabetes

Stem cell treatment for Diabetes

Type 1 diabetes (T1D) is an autoimmune condition associated with a high complication rate. Modern medicine enables patient control the disease; however, complications may still occur, kidney dysfunction, diabetic retinopathy, peripheral neuropathy, and vascular issues to name a few. Despite all the advances in modern medicine there is currently no way to prevent or reverse type 1 diabetes (T1D) with conventional treatments.

Stemwell stem cell therapy for diabetes directly supports the underlying issue, the inability to produce adequate insulin, leading to glucose dysregulation.

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The Condition

Stem cell therapy for Type 1 Diabetes

Type 1 diabetes (T1D), also known as insulin-dependent diabetes, is a chronic autoimmune condition in which the pancreas produces little to no insulin.

Type 1 diabetes develops because the body mistakenly identifies insulin-producing cells (beta cells) as being foreign and not belonging to self. The immune system targets and ultimately destroys the beta cells, resulting in little to no insulin production and the subsequent T1D diagnosis. This autoimmune process is thought to smolder for years, and there are individuals at risk of developing diabetes who do not yet have the diagnosis.

Research has shown, however, that by targeting the tiny blood vessels that oxygenate the pancreas, it is possible to regenerate tissue, promote new vessel growth, and thus sustain and restore insulin production and distribution.

In stem cell treatment for diabetes, mesenchymal stem cells derived from the umbilical cord can support the repair pancreatic tissue repair and insulin-producing cell regeneration.

How Effective Stem Cells are

What is the difference between type 1 and 2 diabetes?

In a healthy person, insulin, which is produced in the pancreas, aids in the absorption of glucose, allowing sugar to be converted into energy or stored for later use. The body relies on insulin to maintain healthy blood sugar levels.

Type 1 diabetes occurs when the body’s immune system destroys the pancreas’s insulin-producing beta cells (b-cells), leaving the body unable to produce insulin on its own.

Type 2 diabetes, the more common form, is distinguished by insulin resistance, a condition in which various tissues in the body no longer respond to the insulin that the pancreas produced. There is a subsequent progressive decline in b-cell function, to the point where the cells no longer produce enough additional insulin to overcome the insulin resistance.

Diabetes is a major problem because it usually leads to other diseases and complications. Regardless of whether your body does not produce insulin (type 1 diabetes) or is insulin resistant (type 2 diabetes), it is not properly regulating your blood-glucose levels. This can lead to long-term complications such as heart disease, stroke, diabetic neuropathy, and kidney failure.

The Advantages

How Stem Cell Treatment for Diabetes works

Stem cells and regenerative cells in combination have been shown to repair cells, increase blood flow, and reduce inflammation. It has also been shown to be effective in supporting healthy immune responses and restoring the body to normal function.

Type 1 diabetes, also known as insulin-dependent diabetes, is a chronic disease in which the pancreas produces little to no insulin and the immune system destroys insulin-producing cells as well as the blood vessels that support them. Stemwell’s stem cells support the repair and regeneration of healthy insulin-producing cells and blood vessels.

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Stemwell Procedures

Stemwell uses umbilical cord tissue-derived mesenchymal stem cells, ethically sourced from full-term human umbilical cords. We may administer 300 million cells that are all thoroughly tested for viability before treatment. These cells are NOT a blood product; therefore, stem cell therapy is safe and does not require HLA or phenotypic matching.

Eligibility

Find out if you qualify for our mesenchymal stem cell (MSC) infusion by completing our secure, HIPAA-compliant qualification form

First Step

The patient undergoes an initial evaluation and blood work by Stemwell’s doctor.

Second Step

Endovenous detox therapy applied to patient 

 

Third Step

Stem Cell IV Infusion Therapy + localized Autologous stem cell injections in trigger pain points under sedation

Fourth Step

  • Hyperbaric Chamber therapy – Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation.
 

Fifth Step

The fifth step is dedicated to addressing diabetes conditions through specialized therapies, including shockwave therapy, ultrasound, magnetotherapy, and laser therapy.

In certain cases, we may also utilize photobiomodulation to address diabetes symptoms or explore its potential benefits.

*Each Protocol is customized to the patient depending their medical and surgical history 

This protocol information is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, is for general information purposes only.

Stem Cells advantages

What are the advantages of stem cell treatment for diabetes with allogeneic umbilical cord tissue-derived stem cells?

Because human umbilical cord mesenchymal stem cells (HUC-MSCs) are immune system privileged, cell rejection is not an issue, and human leukocyte antigen (HLA) matching is not required. We screen and select stem cells with the best anti-inflammatory activity, immune modulating capacity, and ability to stimulate regeneration. Allogeneic stem cells can be administered in uniform doses with high cell counts multiple times over the course of several days.

Umbilical cord tissue provides an abundant supply of MSCs. There is no need to collect stem cells from the patient’s hip bone or fat under anesthesia, which can be a traumatic experience for small children and their parents. A growing body of evidence suggests that MSCs derived from umbilical cord tissue are more robust than MSCs derived from other sources.

There is no need to administer chemotherapy drugs such as Granulocyte-colony stimulating factor (G-CSF or GCSF) to stimulate bone marrow granulocyte and stem cell production and their release into the bloodstream.

Which Type of Stem Cells

Which types of stem cells are used to treat autoimmune diseases and how are they collected?

Stemwell’s adult stem cells are derived from human umbilical cord tissue and are used to treat autoimmune diseases (allogeneic mesenchymal). These stem cells are expanded in our cutting-edge laboratory.

The umbilical cord mesenchymal stem cells (MSCs) we use are recovered from young, healthy donors following normal, healthy births. Each potential donor is vetted and tested for infectious diseases. Prior to donation, each family provides written consent.

Before being approved for use in patients, all umbilical cord-derived stem cells are tested for infectious diseases in accordance with International Blood Bank Standards.

Only a small percentage of donated umbilical cords make it through our stringent screening process.

FAQ

Frequently asked questions on using stem cell therapy for diabetes

Can’t find an answer? Please contact us.

We are happy to help. 

There’s limited research on using stem cells in diabetes specifically, meaning there’s not enough information to say how effective stem cell therapy is for treating diabetes. Because of this, stem cell therapy for diabetes is an experimental approach.

We do know that stem cells have the ability to repair damaged tissues and reduce inflammation. So in theory, stem cells may be able to rejuvenate damaged pancreatic tissues – which can help to stimulate insulin-producing cells. This leads to improved glucose control and reduces dependence on injected insulin.

Some research has demonstrated this effect in people with diabetes. Early transplantation of mesenchymal stem cells (the type of cells we use at Stemwell) has shown to reduce the number of hypoglycemic episodes, produce an anti-inflammatory response, and improve overall quality of life1.

However, more research is needed in this field before the efficacy of stem cell therapy for diabetes can be confirmed.

As stem cell therapy is still considered an experimental treatment approach for diabetes, the long-term safety and effectiveness of the treatment has not been fully established. While mesenchymal stem cell treatments generally pose minimal risks, the possibility of adverse reactions can’t be ruled out. 

At Stemwell, we take a wide range of precautions to minimize these risks. For example, we follow strict guidelines set by the Secretary of Health in Colombia, meaning we only use approved methods and tested techniques. We also rigorously screen all donor stem cells to reduce the chances of any negative reactions. If you have any questions or concerns about stem cell therapy, contact us

Learn more about the pros and cons of stem cell therapy.

The total cost of stem cell therapy can vary greatly between individuals. At Stemwell, we believe in tailoring treatments to the individual, using factors like the severity of the disease, and individual patient health to guide us. From here, we develop bespoke treatment plans that aim for the most effective outcomes for that individual. From this treatment plan we can give an indication of costs.

Stem cells are administered intravenously – where stem cells are injected into your bloodstream through your vein.

Although stem cell therapy may be able to improve the symptoms of diabetes and directly support the underlying issue, it should not be considered a cure. Much more research and development is needed to understand whether it has the potential to be a cure.

You should always follow treatment advice from your trusted healthcare provider.

The time to see results widely depends on your condition and the specific type of therapy used. Tissue repair and regeneration is not a quick process. Some patients might see improvements in a few months after treatment whereas it may take slightly longer for others.

1. Izadi, M., Sadr Hashemi Nejad, A., Moazenchi, M. et al. (2022). Mesenchymal stem cell transplantation in newly diagnosed type-1 diabetes patients: a phase I/II randomized placebo-controlled clinical trial. Stem Cell Res Ther 13, 264.