Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by challenges in social interaction, communication, and repetitive behaviors. Emerging research suggests that neuroinflammation and immune dysregulation may contribute to its pathophysiology (Hughes et al., 2022). At Stemwell Health in Bogotá, Colombia, we are dedicated to exploring advanced, evidence-based therapies, including stem cell therapy, hyperbaric oxygen therapy (HBOT), and integrative physical therapies, to support individuals with ASD.
Stem Cell Therapy: Investigating Potential Benefits
Recent studies have indicated that mesenchymal stem cells (MSCs) have demonstrated immunomodulatory properties that may be relevant in addressing neuroinflammation associated with autism spectrum disorders (ASD). Neuroinflammation, characterized by microglial activation, is a recognized feature in ASD pathology, and MSCs have been explored for their potential to modulate immune responses and reduce inflammation (Tamouza et al., 2022). Clinical studies have also explored the use of MSCs in ASD, with preliminary trials indicating safety and potential improvements in ASD symptoms following MSC infusions (Sun et al., 2020).
Hyperbaric Oxygen Therapy (HBOT): Assessing Its Role in ASD
HBOT involves breathing 100% oxygen in a pressurized chamber, enhancing oxygen delivery to hypoxic brain tissues. Studies have explored its use in ASD, showing that HBOT can improve cerebral perfusion, reduce oxidative stress, and modulate neuroinflammatory markers in children with ASD (Tu et al., 2025) ( Podgórska-Bednarz & Perenc, 2021).
Integrative Physical Therapies: Complementary Approaches
Complementary therapies, including occupational therapy, sensory integration therapy, and neuromotor training, support functional development in children with ASD. These therapies are well-established and widely recommended as part of a comprehensive treatment plan for individuals with ASD (Castaño et al., 2023). These therapies enhance coordination, balance, and sensory regulation—areas often impaired in autism. When combined with regenerative therapies, they may accelerate improvements in cognitive and behavioral outcomes.
Commitment to Evidence-Based Care at Stemwell Health
At Stemwell Health, we prioritize patient safety and the application of therapies grounded in robust scientific evidence. While innovative treatments like stem cell therapy and HBOT are being explored, we emphasize the importance of continued research and adherence to established clinical guidelines. Our multidisciplinary team is dedicated to providing personalized care that integrates the latest scientific insights with proven therapeutic approaches.
Evidence-Based, Multimodal Care at Stemwell Health
Our approach at Stemwell Health integrates:
- MSC infusions tailored to patient profiles
- HBOT protocols with evidence-based pressures and durations
- Clinical evaluation by regenerative medicine experts
- Family-centered outcome tracking using validated behavioral scales
Autism Spectrum Disorder presents multifaceted challenges that necessitate a holistic and individualized treatment strategy. At Stemwell Health, we are committed to staying abreast of emerging research and offering therapies that are both safe and supported by scientific evidence. We advocate for ongoing research to better understand and validate the potential benefits of novel treatments for ASD.
References
Hughes, H., RJMoreno, N., & Ashwood, P. (2022). Innate immune dysfunction and neuroinflammation in autism spectrum disorder (ASD). Brain Behavior and Immunity, 108, 245–254. https://doi.org/10.1016/j.bbi.2022.12.00
Tu, P., Halili, X., Zhang, S., Yang, J., & Xiao, Y. (2025). The effectiveness of hyperbaric oxygen therapy in children and adolescents and with autism spectrum disorders: A systematic review and meta-analysis. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 111257. https://doi.org/10.1016/j.pnpbp.2025.111257
Podgórska-Bednarz, J., & Perenc, L. (2021). Hyperbaric Oxygen Therapy for Children and Youth with Autism Spectrum Disorder: A Review. Brain Sciences, 11(7), 916. https://doi.org/10.3390/brainsci11070916
Castaño, P. R. L., Suárez, D. P. M., González, E. R., Robledo-Castro, C., Hederich-Martínez, C., Cadena, H. P. G., Vargas, P. a. S., & Montenegro, L. C. G. (2023). Effects of Physical Exercise on Gross Motor Skills in Children with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-023-06031-5
Tamouza, R., Volt, F., Richard, J., Wu, C., Bouassida, J., Boukouaci, W., Lansiaux, P., Cappelli, B., Scigliuolo, G. M., Rafii, H., Kenzey, C., Mezouad, E., Naamoune, S., Chami, L., Lejuste, F., Farge, D., & Gluckman, E. (2022). Possible Effect of the use of Mesenchymal Stromal Cells in the Treatment of Autism Spectrum Disorders: A Review. Frontiers in Cell and Developmental Biology, 10. https://doi.org/10.3389/fcell.2022.809686
Sun, J. M., Dawson, G., Franz, L., Howard, J., McLaughlin, C., Kistler, B., Waters-Pick, B., Meadows, N., Troy, J., & Kurtzberg, J. (2020). Infusion of human umbilical cord tissue mesenchymal stromal cells in children with autism spectrum disorder. Stem Cells Translational Medicine, 9(10), 1137–1146. https://doi.org/10.1002/sctm.19-0434
Ready to learn more about stem cell therapy?
At Stemwell, our team of doctors are highly skilled in successfully supporting thousands of people with a range of stem cell treatments. If you would like to learn more about stem cell therapy you can contact us with any questions, or apply today to check your eligibility.
